Advances in breast cancer: What’s new from ESMO 2025

Advances in Breast Cancer: Updates from ESMO 2025

ESMO 2025 highlighted the urgency and breadth of breast cancer research, one of the most diagnosed malignancies worldwide, with major subtypes (HR+, HER2+, and TNBC) responding differently to treatment and developing resistance through distinct mechanisms.

Despite improvements in systemic therapy, long-term survival rates remain suboptimal, and treatment-related toxicities persist. Sequencing also remains uncertain.

This year's ESMO 2025 conference focused on addressing these gaps through targeted combinations, improved tolerability, and biomarker-driven strategies. Notably, the adjuvant use of CDK4/6 inhibitors is redefining the management of high-risk HR+ early-stage disease.

Author's summary: ESMO 2025 updates breast cancer research.

more

pharmaphorum pharmaphorum — 2025-10-30

More News