The error message “To run this application, you first must install one of the following versions of the .NET Framework” appears when attempting to launch a program that depends on specific .NET Framework components.
This error occurs due to missing, corrupted, damaged, or blocked .NET Framework components within Windows. Other possible reasons include:
A single broken or disabled component within the .NET Framework can stop the entire environment from functioning.
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Author's summary: Fix .NET Framework error by identifying causes.