Sperm From Older Men Carry More Genetic Mutations Linked To Childhood Disorders
A Nature study shows sperm from older fathers carry more disease-linked mutations, revealing how age and cell competition shape children’s genetic risks.
Research reveals that sperm cells accumulate genetic mutations eight times slower than blood cells, making them among the most protected cells in the male body.
However, this protection has a critical weakness, one that causes disease-causing mutations to spread through a man’s sperm supply as he ages.
The problem isn’t the mutation rate itself, but rather a form of cellular competition that gives certain harmful mutations a survival advantage.
Author's summary: Sperm from older men carry more genetic mutations.
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